Table 1.
Predictive factors of outcome in HCC
| Patient factors | General medical conditions |
| Performance Status | |
| Quality of life score | |
| Tumor factors | Number, size, total tumor volume |
| Histopathologic grade | |
| Vascular invasion | |
| DNA aneuploidy (DNA index) | |
| Genotype | |
| VEGF levels | |
| Serum AFP | |
| Liver factors | Child Pugh score |
| MELD score | |
| Fibrosis score | |
| Active inflammation | |
| Functional hepatic reserve | |
| Maximal removal rate of glycolated human serum albumin (GSA-Rmax) | |
| Protein induced by vitamin K absence/antagonism II (PIVKA-II serum levels) | |
| Etiology of liver disease | Alcohol |
| Hepatitis B | |
| Hepatitis C | |
| Interactions between patient factors, tumor factors and treatment efficacy |