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. 2010 May 21;116(12):2019–2025. doi: 10.1182/blood-2010-04-277566

Table 1.

Baseline characteristics of optimally and suboptimally followed patients at time of MGUS diagnosis

Variable Optimal (n = 80; 69%) Suboptimal (n = 28; 24%) P
Median age, y (range) 67 (35-87) 67 (50-80) .23
Male sex, n (%) 42 (53) 16 (57) .83
Type of H chain, N (%) .5
    IgG 56 (70) 20 (72)
    IgA 20 (25) 6 (21)
    Light chain 2 (2.5) 0
    Biclonal 2 (2.5) 2 (7)
    Median M spike (range), g/dL 1.5 (undetectable-2.9) 1.3 (undetectable-2.9) .09
    Median hemoglobin (range), g/dL 13.2 (8.7-17) 13.3 (8.9-16.4) .73
    Median calcium (range), mEq/L 9.5 (8.4-11.1) 9.1 (8.5-10.1) .02*
    Median creatinine (range), mg/dL 1.1 (0.6-3.0) 1.1 (0.8-1.4) .44
    Median total protein (range), mg/dL 7.2 (5.8-10.7) 7.1 (5.5-8.4) .11

Of the 116 patients who met study criteria, 8 were excluded from further analysis because of progression to symptomatic MM within one year of MGUS diagnosis. The remaining 108 were divided into 2 categories according to the frequency of follow-up. The optimal category grouped patients who received follow-up every 6 to 36 months. The suboptimal group included patients who were monitored less often than every 36 months or who did not receive follow-up at all. The table shows baseline characteristics of patients in each category at the time of MGUS diagnosis.

*

Statistically significant.