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Effect of lipopolysaccharide (LPS) + mechanical ventilation (MV) on polymorphonuclear neutrophils (PMNs) in bronchoalveolar lavage fluid. PMNs were measured in the BALF from adult and juvenile mice treated with inhaled LPS, MV, and LPS+MV. Values are the mean ± SD (n ≥ 12 per group). ‡ Synergy between LPS and MV in adult mice (P = 2.1 × 10−14), and the horizontal bar indicates the effect of age on the PMN responses to LPS+MV (*P = 8.2 × 10−10).
