Figure 6. Allelic bias is present following ligation-mediated PCR (LM-PCR) but not Multiplexed Linear Amplification (MLA).

(A) Starting from 6.25 ng genomic DNA, electropherogram of a heterozygous sequence at tandem SNP location rs11088086–rs2251447 following LM-PCR. Allele 2 was clearly preferentially amplified. (B) Starting from 6.25 ng genomic DNA, electropherogram of a heterozygous sequence at tandem SNP location rs11088086–rs2251447 following MLA. No allelic bias was observed for MLA with six assays.