. 2010 Oct 8;5(10):e13186. doi: 10.1371/journal.pone.0013186

Table 3. The relative abundance of the identified compounds/peaks differentiating UCML from HC and the regulation by imatinib.

Variable Name	Healthy control(HC)			UCML				Fold change	SCML					RCML
	Mean	±	SD	Mean	±	SD		UCML/HC	Mean	±	SD			Mean	±	SD
Pipecolate	66738	±	27812	191019	±	150758		2.864	113166	±	69717			164293	±	105135	^*
Glutamine	397746	±	178241	731628	±	477666	^*	1.839	642994	±	256423		^*	744690	±	508088	^*
myo-Inositol	2567687	±	1211442	4224531	±	2076166	^*	1.645	2460364	±	851377	††		3201257	±	2305927
Arabinose	160888	±	54011	263240	±	134590	**	1.636	169357	±	57379	^†		206307	±	106486
Glycine	4994510	±	1934972	7755324	±	3431521	^*	1.553	5697956	±	1783735			7589657	±	3502635
Urea^§ (mmol/L)	4.95	±	0.94	7.38	±	1.12	^*	1.491	5.10	±	1.21			7.49	±	1.41	^*
Ornithine	7051554	±	3092520	10132171	±	3809942	^*	1.437	9154095	±	4566462			10755744	±	5278905
Pseudouridine	187540	±	93536	262470	±	132366		1.400	123979	±	55572	^†		230273	±	142358
Glutamate	486771	±	129371	672095	±	230155	^*	1.381	475953	±	94505	^†		591183	±	252764
Pyroglutamate	12872691	±	3860744	17366747	±	3905589	**	1.349	14246015	±	3677287	^†		16553496	±	3610300	^*
Urate	8635673	±	5325414	9311846	±	5403118		1.078	11613451	±	3705793			9157485	±	3361998
CPU_ DB5_RI1341_P	66738	±	27812	191019	±	99008	^*	2.862	113166	±	69717			164293	±	105135
Citrate	9277095	±	2814476	7138455	±	2012240	^*	−1.300	8736984	±	1696040			7197272	±	2641511
alpha-Tocopherol	808681	±	165795	601033	±	195359		−1.345	683782	±	282667			535638	±	240045	^*
Linoleate	8552168	±	3885328	5109234	±	2596822	^*	−1.400	6439932	±	3154482			5584365	±	3110760
Adipate	202105	±	130022	135086	±	105583		−1.495	164819	±	69713			168152	±	82656
HDL ^§ (mmol/L)	1.38	±	0.33	0.83	±	0.25	**	−1.663	1.27	±	0.26	^†		0.87	±	0.39
Total cholesterol^§ (mmol/L)	4.57	±	1.28	3.28	±	1.03		−1.393	3.79	±	0.60			2.76	±	0.77
Non-esterified cholesterol	66222510	±	11227958	61596173	±	12264833		−1.075	59449993	±	10150252			55116351	±	10009437
CPU_ DB5_RI2494_P	4252017	±	1132727	3208128	±	1021383	^*	−1.325	4008764	±	1149047	^†		3019455	±	826266	**	^‡
CPU_ DB5_RI2664_P	988481	±	549499	648226	±	389483	^*	−1.525	1080495	±	309271	^†		728768	±	315890		^‡
CPU_ DB5_RI2124_P	177008	±	101696	105477	±	98053		−1.678	186469	±	97861	^†		110002	±	57932

All peaks areas were normalized by the stable isotope internal standard, [¹³C₂]-myristic acid; CPU_ DB5_RIx_P: Unidentified compounds in plasma samples detected with DB-5 capillary column in GC/TOFMS, China Pharmaceutical university (CPU); RI, retention index; x, retention time index value; P, plasma sample.

,**: statistically significant different from that in HC, p<0.05, 0.01;

^†

, ††: statistically significant different from that in UCML, p<0.05, 0.01;

^‡

, ‡‡: statistically significant different from that in SCML, p<0.05, 0.01.

^§

, clinic measurement results.