TABLE 1.
Numbers of Deaths Associated With Autoimmune Diseases as an Underlying Cause or an Underlying or Contributory Cause (Any Mention) of Death Among Females Aged 1 Year or Older: England and Wales, 2003
Aged 1–14 Years |
Aged 15–34 Years |
Aged 35–54 Years |
Aged 55–74 Years |
Aged ≥ 75 Years |
Overalla |
|||||||
Underlying | Any Mention | Underlying | Any Mention | Underlying | Any Mention | Underlying | Any Mention | Underlying | Any Mention | Underlying | Any Mention | |
Addison's disease | 0 | 0 | 0 | 1 | 3 | 10 | 2 | 26 | 11 | 52 | 16 | 89 |
Ankylosing spondylitis | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 8 | 0 | 2 | 2 | 10 |
Autoimmune hemolytic anemia | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 17 | 17 | 50 | 21 | 68 |
Autoimmune thrombocytopenic purpura | 0 | 0 | 0 | 0 | 0 | 1 | 4 | 8 | 11 | 35 | 15 | 44 |
Bullous autoimmune disease | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 9 | 31 | 113 | 36 | 123 |
Celiac disease | 0 | 0 | 0 | 1 | 0 | 4 | 4 | 18 | 12 | 37 | 16 | 60 |
Chronic active hepatitis | 0 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 1 | 1 | 4 | 5 |
Dermatomyositis/polymyositis | 0 | 0 | 0 | 0 | 1 | 2 | 4 | 15 | 15 | 24 | 20 | 41 |
Glomerulonephritis | 0 | 1 | 2 | 3 | 4 | 15 | 19 | 57 | 43 | 86 | 68 | 162 |
Goodpasture's syndrome | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4 | 5 | 5 | 8 | 10 |
Graves’ disease | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 1 | 3 |
Guillain–Barré syndrome | 0 | 0 | 0 | 0 | 1 | 3 | 4 | 6 | 15 | 25 | 20 | 34 |
Idiopathic fibrosing alveolitis | 0 | 1 | 3 | 6 | 22 | 39 | 275 | 487 | 617 | 1035 | 917 | 1568 |
Inflammatory bowel disease | 0 | 0 | 7 | 8 | 16 | 35 | 67 | 144 | 174 | 334 | 264 | 521 |
Insulin-dependent diabetes mellitus | 2 | 2 | 22 | 44 | 24 | 61 | 79 | 260 | 111 | 414 | 238 | 781 |
Juvenile idiopathic arthritis | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 2 |
Lambert–Eaton myasthenic syndrome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple sclerosis | 0 | 0 | 8 | 14 | 199 | 268 | 319 | 495 | 138 | 235 | 664 | 1012 |
Myasthenia gravis | 1 | 1 | 0 | 3 | 2 | 4 | 4 | 7 | 29 | 45 | 36 | 60 |
Myocarditis | 11 | 12 | 16 | 20 | 25 | 53 | 30 | 127 | 40 | 307 | 122 | 519 |
Pernicious anemia | 0 | 0 | 0 | 2 | 0 | 1 | 1 | 10 | 24 | 108 | 25 | 121 |
Polyendocrine syndromes | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Primary biliary cirrhosis | 0 | 0 | 0 | 1 | 7 | 9 | 47 | 81 | 57 | 90 | 111 | 181 |
Psoriasis | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 5 | 9 | 26 | 11 | 32 |
Relapsing polychondritis | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Rheumatic fever/heart disease | 0 | 0 | 4 | 5 | 27 | 48 | 252 | 445 | 552 | 1207 | 835 | 1705 |
Rheumatoid arthritis | 0 | 0 | 1 | 2 | 14 | 34 | 197 | 636 | 489 | 1310 | 701 | 1982 |
Scleroderma/systemic sclerosis | 1 | 1 | 3 | 4 | 8 | 14 | 60 | 91 | 34 | 62 | 106 | 172 |
Sjögren's disease | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 11 | 2 | 9 | 5 | 21 |
Systemic lupus erythematosus | 2 | 2 | 11 | 14 | 19 | 31 | 29 | 53 | 11 | 23 | 72 | 123 |
Thyroiditis | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 0 | 2 | 1 | 5 |
Uveitis | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vasculitis | 0 | 0 | 2 | 2 | 4 | 5 | 24 | 42 | 31 | 49 | 61 | 98 |
Vitiligo | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unspecified autoimmune disease | 0 | 0 | 1 | 3 | 6 | 11 | 7 | 12 | 7 | 14 | 21 | 40 |
Total deathsb | 17 | 20 | 81 | 128 | 385 | 625 | 1450 | 2938 | 2487 | 5560 | 4420 | 9271 |
Seven females aged ≤ 1 year and 3 females with no International Classification of Diseases codes on their death certificates were excluded from the analyses.
In total, 316 females had 2 autoimmune disorders listed on their death certificates, and 7 females had 3 disorders listed; hence, column totals are less than the sum of the counts for individual autoimmune disorders.