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. Author manuscript; available in PMC: 2010 Oct 8.
Published in final edited form as: Int J Tuberc Lung Dis. 2009 Jan;13(1):84–92.

Table 2.

Incidence of TST and QFT conversions among household contacts with concordant negative results at baseline

Criteria for conversion Number with repeated tests* Conversions n Annual incidence of conversions % 95%CI
TST
 Baseline TST < 10 mm, repeat TST ≥ 10 mm, plus a 6 mm increase over the baseline 80 11 13.8 7–23
 Baseline TST < 10 mm, repeat TST ≥ 10 mm, plus a 10 mm increase over the baseline 80 6 7.5 3–16
QFT
 Baseline IFN-γ < 0.35 IU/ml, repeat IFN-γ ≥ 0.35 IU/ml 85 18 21.2 13–31
 Baseline IFN-γ < 0.35 IU/ml, repeat IFN-γ ≥ 0.35 IU/ml, plus a 30% increase over the baseline 85 18 21.2 13–31
 Baseline IFN-γ < 0.35 IU/ml, repeat IFN-γ ≥ 0.35, plus an absolute increase of 0.35 IU/ml over the baseline 85 15 17.6 10–27
 Baseline IFN-γ < 0.35 IU/ml, repeat IFN-γ ≥ 0.70 IU/ml 85 10 11.8 6–20
*

Only contacts with baseline concordant negative (QFT-negative/TST-negative) results were included in this analysis.

TST = tuberculin skin test; QFT = QuantiFERON-TB Gold In-Tube®; CI = confidence interval; IFN-γ = interferon-gamma.