Figure 2.

Representative images of fluorescence yield overlying the corresponding MR images. Each column provides results for a single animal from one of the three mouse populations (U251 tumors, 9L tumors, and controls, respectively). The rows show images recovered using the hard-prior technique (I), the soft-prior technique (II), and an unguided reconstruction technique that operates under the assumption that only the outer boundary was known (III). Given the wide range of recovered values between subjects, the color scales were kept consistent only within the image set for each animal. Transparency levels were varied between images to ensure that the MR images are easily discerned through the optical image overlay. (Color online only.)