Table 3.
Univariate survival analysis
| Predictor | Level | Median Survival (days) | 95% CI | Hazard Ratio | P-value |
|---|---|---|---|---|---|
| PF4 | Continuous (N = 133) | 323 | 283 – 385 | 1.08 | 0.003 |
| PF4* | ≤ 11 kU/ml (N = 65) | 389 | 313 – 467 | 1.00 | --- |
| >11 kU/ml (N = 68) | 254 | 203 – 343 | 1.77 | 0.004 | |
| Age | Continuous (N = 133) | 323 | 283 – 385 | 1.024 | 0.005 |
| Class* | N0 (N = 32) | 401 | 289 – 929 | --- | --- |
| N1 (N = 51) | 402 | 336 – 455 | 1.27 | 0.37 | |
| M1 (N = 50) | 170 | 116 – 314 | 2.85 | <0.0001 | |
| Gender* | Female (N = 60) | 254 | 189 – 367 | --- | --- |
| Male (N = 73) | 374 | 291 – 448 | 0.61 | 0.013 | |
| Platelet Count | Continuous (N = 124) | 323 | 283 – 385 | 0.23 | 0.82 |
| Stage* | IA, I, IIA (N = 27) | 401 | 255 - ∞ | --- | |
| IIB (N = 34) | 402 | 343 – 467 | 1.50 | 0.19 | |
| III (N = 23) | 336 | 283 - ∞ | 1.53 | 0.20 | |
| IV (N = 49) | 170 | 116 – 314 | 3.22 | <0.0001 | |
| Treatment* | No (N = 54) | 283 | 179 – 411 | --- | --- |
| Yes (N = 76) | 343 | 291 – 400 | 0.99 | 0.94 |
*
Categorical variables were treated as ordered with the first level assigned as the reference