Table I.
Characteristic | Case-patient | |||||
---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | |
Gender | Female | Male | Female | Male | Female | Male |
Age (years) | 86 | 74 | 62 | 67 | 92 | 90 |
Underlying condition | Lymphoma | Liver cirrhosis (Child's class C) |
Lymphoma | Liver cirrhosis (Child's class B) |
Cardiac disease | Cardiac disease |
Reason for admission | Febrile neutropenia | Liver failure and gastrointestinal bleeding | Intestinal obstruction | Liver failure | Heart failure and pneumonia | Heart failure |
Ward of admission | Hematology | Internal medicine | Hematology | Internal medicine | Internal medicine | Internal medicine |
Type of listeriosis | Primary bacteremia | Primary peritonitis | Secundary bacteremia | Primary peritonitis | Secondary bacteremia | Secondary bacteremia |
Symptoms | Fever | Fever | Diarrhea, abdominal pain and fever | Fever | Diarrhea, abdominal pain and fever | Diarrhea and fever |
Listeria serotype | NA | 3b | 1/2b | 1/2b | 1/2b | 1/2b |
Presence of neutropenia | Yes | No | Yes | No | No | No |
Type of nutrition | Oral | Oral | Oral | Oral | Oral/Enteral | Oral |
Time (days) from | ||||||
admission to listeriosis onset | 0* | 10 | 9 | 14 | 8 | 7 |
listeriosis onset to culture result | 5 | 4 | 9 | 2 | 7 | 4 |
listeriosis onset to outcome | 1 | 1 | 26 | 10 | 10 | 3 |
Antibiotic therapy | ||||||
Empirical | Cefepime | Ceftriaxone | Cefepime plus metronidazole | Ceftriaxone | Cefepime | None |
After culture result | ** | ** | Ampicillin | Ceftriaxone | Ampicillin | ** |
Patient outcome | Death | Death | Death | Discharge | Death | Death |
NA: isolate not available;
patient had undergone chemotherapy in the hematologic day-clinic during the previous three months;
patient died before culture result was available