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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Bioorg Med Chem. 2010 May 7;18(13):4801–4811. doi: 10.1016/j.bmc.2010.05.001

Figure 9.

Figure 9

Stability of compounds (1 µM) in CD-1 female mouse liver microsomes at 37°C. Panel A: phenol compounds and parent scaffold ketoprofen (7). Panel B: indole compounds. Half-lives are estimated as 2.8 h (23), 0.6 h (26), 1.8 h (33), and 0.8 h (42).