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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Bioorg Med Chem. 2010 May 7;18(13):4801–4811. doi: 10.1016/j.bmc.2010.05.001

Table 5.

Caco2 cell permeability of selected compounds at pH7.4. Digoxin served as a control.

compound average Papp
A→B (nm/s)		 average Papp
B→A (nm/s)		 efflux ratio
(B→A)/
(A→B)
5 130 58 0.45
23 122 39 0.31
26 58 27 0.46
digoxin 80 92 1.15