Table 1.

Apoptosis

Cell signaling agent	Organ or action	Reference
(1) MAP kinases	Human breast cancer cell MCF-11	47
(2) Fas redistribution in the rafts	Colon cancer cells	48
(3) Ceramide	Breast cancer cells	49
(4) STAT3 and nuclear factor-κB-regulation	Human multiple myceloma cells	50
(5) Protein kinases and p38 kinase	Antitumor activity	51
(6) Src and Stat3	Breast cancer	52
(7) TRAIL-induced	Mitochondria	53
(8) Phosphorylated Akt and Caspace-9	MCF7 human breast cancer cells	54
(9) Cdc42 activation of ASK1/JNK	Human leukemia cancer cells	55
(10) Phosphatidylinositol 3′-kinase Akt	Human prostate cancer cells	56
(11) WAF-1/p21-mediated G1 phase	Human epidermoid Carcinoma A431 cells	57
(12) AMPK	Colon cancer cells	58
(13) JNK and c-JUN/AP-1	Prevented HNE-induced JNK	59
(14) c-Myc	Downregulation in human medulloblastoma	60
(15) ERK	Initiates p53 dependent apoptosis via αVβ3	61
(16) Caspase-3	Human breast cancer cell	62
(17) CD95	Human tumor cells	63
(18) TNBS	Inhibiting Notch pathway	64
(19) p53 and P13K/Akt	Human T-cell acute lymphoblastic leukemia MOLT-4 cells	65