Table 2.

Mortality with and without patients with missing deferred consent

	Control group	Lactate group	Relative risk (95% CI)	p-Value
In-hospital mortality: unadjusted analysis, % (n)
All patients (n = 348)	43.5 (77/177)	33.9 (58/171)	0.78 (0.60−1.02)	0.067
Excluding early death (n = 309)	33.8 (51/151)	28.5 (45/158)	0.84 (0.60−1.18)	0.32
Excluding all missing deferred consent (n = 289)*	33.1 (46/139)	28.7 (43/150)	0.87 (0.61−1.22)	0.42
In-hospital mortality: adjusted analysis, hazard ratio (95% CI)
All patients (n = 348)		0.61 (0.43−0.87)		0.006
Excluding early death (n = 309)		0.80 (0.53−1.21)		0.28
Excluding all missing deferred consent (n = 289)		0.81 (0.53−1.25)		0.35

* p-Value for interaction between consent status (missing or obtained consent) and treatment effect (Breslow–Day test of homogeneity): 0.59