Table 1.

Biomimetic Vascular Network Design Principles to Achieve Physiologic Blood Flow in Tissue Engineering Scaffolds and Tissue-Specific Design Inputs to Tailor the Flow and Architecture to Meet the Metabolic Demands of a Particular Tissue

Biomimetic vascular network design principles	Tissue-specific vascular network design inputs
1. Defined relationship between parent and daughter diameters	1. Tissue-specific architecture
2. Physiologic branching angle	2. Inlet pressure
3. Biomimetic vessel length	3. Outlet pressure
4. 1:1 aspect ratio for all vascular channels	4. Volume flow rate
5. Venous scaling	5. Channel density
6. Uniform flow at bifurcations
7. Physiological shear stress