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. 2010 Jul 28;285(42):32174–32181. doi: 10.1074/jbc.M109.091850

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — SPINK6 is expressed in the skin and its appendages. Immunohistochemical analyses using an affinity-purified goat anti-SPINK6 polyclonal antibody revealed localization of SPINK6 within the stratum granulosum of the epidermis and stratum corneum (A, C, and D). Exemplary anatomical localizations of the samples were the face (A), plantar site (C), and upper arm (D). In B, the control is shown when rSPINK6 (0.5 μg/ml) was used to block the antibody (same paraffin sample as in A). Sebaceous glands showed positive staining (E), and some sweat glands exhibited immunoreactive SPINK6 (F).