Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Aug 2;285(42):32476–32485. doi: 10.1074/jbc.M110.141028

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 5. — Changes in SLs after bSMase treatment in HeLa cells. A, the SL profile of HeLa cells was measured in serum-free conditions. C₁₆ (red), C_24:1 (blue), and C₂₄ were the main acyl chains among the different acyl chain species analyzed. Sph and S1P and their dihydro (dh) forms were also measured. B, levels of SM and ceramide species. After bSMase treatment (25 milliunits (mU)/ml, 10 min), the SL profile was monitored, and only SL species that underwent significant changes are presented (red, LC species; blue, VLC species): Sphingomyelin (B) and ceramide (C) species. GlcCeramide, glucosyl ceramide; LacCeramide, lactosyl ceramide; Cer, ceramide.