Figure 7.

Adrenergic receptor blockade increases ventricular sympathetic innervation after coronary artery ligation. Quantitative analyses of dopamine β-hydroxylase-immunoreactive innervation shows that regions of the ventricular myocardium remote to the infarct (Non-ischemic) have relatively low innervation density in saline-infused rats (S; n = 4), and this was increased by propranolol (Pr; n = 4) but not by phentolamine (Ph; n = 4). Neither propranolol nor phentolamine altered the relatively high innervation density characteristic of the infarct border. Results are presented as the mean ± SEM. *p < 0.05 versus saline.