Figure 7.
(A) Structure of the water-soluble Au NPs as a PDT drug delivery agent, Pc 4 structure (B) Fluorescence images of a tumor-bearing mouse after being injected with Au NP-Pc 4 conjugates in normal saline (0.9% NaCl, pH 7.2), (a) 1 min, (b) 30 min, and (c) 120 min after intravenous tail injection. Any bright signal is due to Pc 4 fluorescence. For comparison, a mouse that got only a Pc 4 formulation without the Au NP vector injected is shown in panel (d). No circulation of the drug in the body or into the tumor was detectable 2 h after injection without the Au NP as drug vector. Reprinted with permission from Ref. 80.