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Intramacrophage survival of F. novicida acid phosphatase mutants in BMDMs from p47phox+/+ and p47phox−/− knockout mice. BMDMs were isolated from p47phox+/+ WT C57BL/J mice (A) and p47phox−/− knockout mice C57BL/J (B) infected with F. novicida or the mutant derivatives acpA or ΔABCH. Data are the mean ± SD of triplicate samples from one representative experiment (n = 3).
