Table 4.
Effect of a forty-day oral administration of Corrigiola telephiifolia extract on hematological parameters of Wistar rats.
| Corrigiola telephiifolia (mg/kg/day) | |||||
|---|---|---|---|---|---|
| Control | 5 | 70 | 2000 | ||
| Females | Parameter | ||||
| WBC (103/mm3) | 6.2 ± 0.6 | 6.0 ± 0.5 | 5.9 ± 0.5 | 5.9 ± 0.9 | |
| RBC (106/mm3) | 6.2 ± 0.4 | 6.2 ± 0.3 | 6.5 ± 0.4 | 6.2 ± 0.3 | |
| HGB (g/dL) | 10.7 ± 0.7 | 10.8 ± 0.6 | 11.2 ± 0.6 | 10.3 ± 0.4 | |
| HCT (%) | 33.3 ± 2.3 | 33.5 ± 2.3 | 35.2 ± 2.3 | 32.2 ± 1.6 | |
| PLT (103/mm3) | 143.0 ± 13.5 | 145.0 ± 15.1 | 151.7 ± 19.5 | 146.4 ± 14.2 | |
| MCV (μm3) | 54.2 ± 1.0 | 54.2 ± 0.9 | 54.3 ± 0.6 | 52.1 ± 0.4 | |
| MCH (pg) | 17.4 ± 0.3 | 17.4 ± 0.2 | 17.3 ± 0.15 | 16.6 ± 0.3 | |
| MCHC (g/dL) | 32.1 ± 0.2 | 32.0 ± 0.3 | 32.0 ± 0.3 | 32.0 ± 0.3 | |
| RDW (%) | 13.2 ± 0.3 | 13.3 ± 0.3 | 13.3 ± 0.2 | 13.7 ± 0.3 | |
| MPV (μm3) | 9.1 ± 0.8 | 9.2 ± 0.5 | 10.2 ± 0.5 | 9.3 ± 1.0 | |
|
| |||||
| Males | |||||
| WBC (103/mm3) | 7.4 ± 1.5 | 6.8 ± 0.9 | 6.4 ± 0.7 | 6.8 ± 0.9 | |
| RBC (106/mm3) | 6.6 ± 0.3 | 6.5 ± 0.4 | 6.4 ± 1.0 | 7.8 ± 0.9 | |
| HGB (g/dL) | 10.8 ± 0.4 | 10.7 ± 0.8 | 10.3 ± 1.5 | 12.2 ± 1.1 | |
| HCT (%) | 34.9 ± 1.5 | 34.5 ± 1.9 | 32.9 ± 5.4 | 41.1 ± 4.9 | |
| PLT (103/mm3) | 158.2 ± 11.3 | 149.4 ± 13.2 | 124.8 ± 14.6 | 136.2 ± 19.2 | |
| MCV (μm3) | 53.2 ± 0.7 | 52.3 ± 0.6 | 51.6 ± 0.8 | 52.8 ± 0.6 | |
| MCH (pg) | 16.5 ± 0.2 | 16.2 ± 0.2 | 16.2 ± 0.3 | 15.8 ± 0.4 | |
| MCHC (g/dL) | 31.0 ± 0.4 | 31.2 ± 0.5 | 31.6 ± 0.7 | 30.1 ± 0.8 | |
| RDW (%) | 14.0 ± 0.7 | 13.7 ± 0.4 | 13.6 ± 0.3 | 13.8 ± 0.4 | |
| MPV (μm3) | 7.0 ± 1.5 | 7.2 ± 0.5 | 7.5 ± 0.4 | 8.1 ± 0.4 | |
C. telephiifolia extract was administered daily for 40 consecutive days to rats (n = 8). Data are expressed as mean ± S.E.M. There were no statistically significant differences between control and treated groups.