Table 5.
Effect of a forty-day oral administration of Corrigiola telephiifolia extract on biochemical parameters of female Wistar rats.
| Corrigiola telephiifolia (mg/kg/day) | ||||
|---|---|---|---|---|
| Control | 5 | 70 | 2000 | |
| Parameter | ||||
| Na mmol/L | 149.4 ± 0.7 | 148.0 ± 0.5 | 141.6 ± 1.0* | 136.1 ± 1.7* |
| Cl mmol/L | 117.3 ± 0.5 | 116.4 ± 0.3 | 110.1 ± 0.7* | 106.3 ± 1.1* |
| K mmol/L | 8.5 ± 0.5 | 8.2 ± 0.6 | 7.8 ± 0.5 | 9.3 ± 0.9 |
| Mg mmol/L | 1.6 ± 0.2 | 1.5 ± 0.2 | 1.5 ± 0.1 | 1.4 ± 0.1 |
| Ca mmol/L | 2.2 ± 0.2 | 2.1 ± 0.2 | 2.0 ± 0.1 | 2.0 ± 0.1 |
| Iron μmol/L | 51.6 ± 4.4 | 52.3 ± 3.7 | 53.6 ± 2.8 | 46.7 ± 4.0 |
| Ph.org mmol/L | 3.2 ± 0.2 | 3.3 ± 0.4 | 3.8 ± 0.5 | 4.3 ± 0.4* |
| Total Protein g/L | 75.4 ± 1.0 | 74.1 ± 1.2 | 70.9 ± 2.0 | 69.1 ± 1.6* |
| Glucose mmol/L | 8.0 ± 1.0 | 7.5 ± 0.8 | 6.7 ± 0.5 | 6.4 ± 1.0 |
| Urea mmol/L | 6.6 ± 0.2 | 6.3 ± 0.5 | 5.6 ± 0.5 | 6.0 ± 0.4 |
| Creatinine μmol/L | 26.4 ± 5.1 | 25.7 ± 1.3 | 22.9 ± 1.2 | 87.0 ± 15.6* |
| Bicarbonates mm Hg | 16.0 ± 1.8 | 15.4 ± 1.1 | 14.0 ± 1.5 | 20.9 ± 2.1 |
| Uric acid μmol/L | 194.5 ± 59.7 | 183.7 ± 35.2 | 177.3 ± 43.6 | 175.6 ± 50.1 |
| Total cholesterol mmol/L | 1.7 ± 0.1 | 1.7 ± 0.1 | 1.6 ± 0.1 | 1.4 ± 0.1 |
| Triglycerides mmol/L | 1.8 ± 0.3 | 1.7 ± 0.2 | 1.7 ± 0.2 | 1.3 ± 0.3 |
| Bilirubin μmol/L | 25.4 ± 2.5 | 25.0 ± 2.4 | 24.4 ± 2.1 | 27.4 ± 2.9 |
| AST UI/L | 54.5 ± 6.1 | 55.1 ± 6.0 | 57.7 ± 6.2 | 78.5 ± 21.8 |
| ALT UI/L | 20.2 ± 1.7 | 21.3 ± 2.5 | 27.1 ± 5.0 | 33.7 ± 8.6 |
| ALP UI/L | 121.7 ± 10.8 | 115.9 ± 7.5 | 103.0 ± 9.9 | 202.1 ± 30.0* |
| GGT UI/L | 1.4 ± 0.1 | 1.4 ± 0.2 | 1.5 ± 0.2 | 1.9 ± 0.2* |
C. telephiifolia extract was administered daily for 40 consecutive days to rats (n = 8). Data are expressed as mean ± S.E.M.
*Significantly different from the control (P < .05).