Table 6.
Effect of a forty-day oral administration of Corrigiola telephiifolia extract on biochemical parameters of male Wistar rats
| Corrigiola telephiifolia (mg/kg/day) | ||||
|---|---|---|---|---|
| Control | 5 | 70 | 2000 | |
| Parameter | ||||
| Na mmol/L | 140.9 ± 0.6 | 139.5 ± 0.3 | 138.3 ± 0.6* | 135.1 ± 1.3* |
| Cl mmol/L | 111.3 ± 0.6 | 110.7 ± 0.2 | 105.0 ± 0.5* | 103.4 ± 0.4* |
| K mmol/L | 8.0 ± 0.3 | 8.0 ± 0.4 | 8.0 ± 0.5 | 7.7 ± 0.4 |
| Mg mmol/L | 1.5 ± 0.1 | 1.6 ± 0.1 | 1.9 ± 0.1 | 1.4 ± 0.1 |
| Ca mmol/L | 1.7 ± 0.1 | 1.7 ± 0.1 | 1.9 ± 0.1 | 1.8 ± 0.1 |
| Iron μmol/L | 28.9 ± 1.6 | 28.7 ± 1.5 | 28.6 ± 2.2 | 32.7 ± 2.3 |
| Ph.org mmol/L | 4.4 ± 0.4 | 4.3 ± 0.4 | 4.1 ± 0.4 | 4.5 ± 0.5 |
| Total protein g/L | 66.4 ± 1.2 | 66.5 ± 1.0 | 67.9 ± 1.1 | 66.6 ± 1.7 |
| Glucose mmol/L | 6.6 ± 0.2 | 6.5 ± 0.3 | 6.4 ± 0.4 | 6.9 ± 0.5 |
| Urea mmol/L | 5.0 ± 0.3 | 5.1 ± 0.2 | 5.1 ± 0.2 | 4.7 ± 0.3 |
| Creatinine μmol/L | 23.2 ± 1.7 | 23.1 ± 0.9 | 23.0 ± 0.7 | 26.8 ± 2.0 |
| Bicarbonates mm Hg | 21.3 ± 0.8 | 21.5 ± 0.7 | 22.1 ± 1.0 | 20.6 ± 1.3 |
| Uric acid μmol/L | 271.1 ± 29.2 | 264.8 ± 24.5 | 251.4 ± 21.4 | 200.9 ± 35.8 |
| Total cholesterol mmol/L | 1.5 ± 0.1 | 1.5 ± 0.1 | 1.4 ± 0.1 | 1.7 ± 0.1 |
| Triglycerides mmol/L | 1.2 ± 0.1 | 1.2 ± 0.1 | 1.1 ± 0.1 | 1.2 ± 0.2 |
| Bilirubin μmol/L | 27.5 ± 1.3 | 27.8 ± 1.4 | 28.1 ± 1.5 | 31.9 ± 2.0 |
| AST UI/L | 77.9 ± 6.9 | 79.5 ± 7.3 | 81.9 ± 7.1 | 114.5 ± 23.5 |
| ALT UI/L | 25.0 ± 1.4 | 24.7 ± 1.5 | 22.2 ± 1.3 | 41.3 ± 9.6 |
| ALP UI/L | 146.3 ± 23.6 | 153.6 ± 21.3 | 164.1 ± 15.8 | 173.4 ± 28.3 |
| GGT UI/L | 1.5 ± 0.2 | 1.5 ± 0.1 | 1.4 ± 0.1 | 2.2 ± 0.4 |
C. telephiifolia extract was administered daily for 40 consecutive days to rats (n = 8). Data are expressed as mean ± S.E.M.
*Significantly different from the control (P < .05).