Table 2.
Significantly changed genes following treatment with 3 μM of PEITC (n = 4, *P < .05, ***P < .001). Results are expressed as fold change as compared to vehicle controls and represent the average of five independent microarray experiments.
| Gene name | Description | Fold ± S.D. |
|---|---|---|
| p57 | cyclin-dependent kinase inhibitor 1C | 5.23*± 2.74 |
| CYP19 | cytochrome P450, subfamily XIX | 5.22***± 0.988 |
| BRCA2 | Breast Cancer 2, early-onset | 4.22*± 2.30 |
| IL-2 | Interleukin-2, T-cell growth factor | 3.16*± 1.22 |
| ATF2 | Activating Transcription Factor 2 | 2.60*± 0.900 |
| p53 | Tumor protein p53 | 2.12*± 1.46 |
| Hsp27 | Heat shock 27 KD protein | 1.84*± 0.409 |