Table 1.
Immunomodulatory activity of ACS on Humoral (Antibody titre) and cell-mediated immune response (CMI) in normal Balb/c mice.
| Test material | Dose mg/kg p.o. |
Humoral response antibody titre mean ± S.E. |
CMI response foot thickness (mm) 24 h mean ± S.E. |
|---|---|---|---|
| Control | — | 6.18 ± 0.36 | 0.68 ± 0.06 |
| ACS | 1.56 | 7.03 ± 0.11 (13.91↑) |
0.74 ± 0.28 (8.82↑) |
| ACS | 3.12 | 7.10 ± 0.28 (14.88↑) |
0.75 ± 0.38 (10.29↑) |
| ACS | 6.25 | 8.03 ± 0.43** (29.93↑) |
0.78 ± 0.30* (14.70↑) |
| ACS | 12.50 | 8.01 ± 0.56** (29.61↑) |
0.77 ± 0.13 (13.23↑) |
| ACS | 25.00 | 7.63 ± 0.48** (23.46↑) |
0.76 ± 0.43 (11.76↑) |
| ACS | 50.00 | 7.40 ± 0.56* (19.74↑) |
0.73 ± 0.48 (7.35↑) |
| Levamisole | 2.5 | 8.39 ± 0.16** (35.76↑) |
0.88 ± 0.18** (29.14↑) |
| Cyclosporine | 5.00 | 3.92 ± 0.31** (36.56↓) |
0.42 ± 0.13** (38.23↓) |
Value in parentheses signify percentage activity in agglutinating antibody titre and CMI Response
↓ : Percent Decrease, ↑ : Percent Increase
n = 6,
All values are shown as Mean ± S.E.
P-value:* < .01;** < .001,
P-values were calculated by Student's t.