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. Author manuscript; available in PMC: 2011 Sep 14.
Published in final edited form as: Circulation. 2010 Sep 14;122(11 Suppl):S124–S131. doi: 10.1161/CIRCULATIONAHA.109.928424

Figure 6.

Figure 6

Endogenous regulation of Efna3 and Ptp1b by miR-210. (A) Quantitative RT-PCR indicate miR-210 can inhibit Efna3 but not Ptp1b at the RNA level. Student’s t-test was used. (B) However, Western blotting showed Ptp1b can be inhibited at the protein level instead. Student’s t-test was used. (C) Immunofluorescence confirmed miR-210 can strongly diminish Efna3 and Ptp1b expression in HL-1 cardiomyocytes. (D) Western blot data show that Efnas and Ptp1b from the peri-infarct regions of explanted hearts are significantly lower in the MC-210 group compared to MC-Scr group. Student’s t-test was used. *P<0.05.