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. Author manuscript; available in PMC: 2012 Jul 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2010 Jul 7;80(4):1015–1022. doi: 10.1016/j.ijrobp.2010.03.012

Table 2.

Mean critical total lung volumes received on the photon SBRT, PSPT, and IMPT plans

Critical Lung Volumes Photon SBRT PSPT p* IMPT p p
Mean total lung dose, Gy (SE) 5.4 (0.5) 3.5 (0.4) < 0.001 2.8 (0.3) < 0.001 < 0.001
Mean total lung V5, % (SE) 22.9 (2.1) 11.4 (1.1) < 0.001 10.0 (1.1) < 0.001 0.001
Mean total lung V10, % (SE) 15.2 (1.5) 10.3 (1.0) < 0.001 8.2 (1.0) < 0.001 < 0.001
Mean total lung V20, % (SE) 8.7 (1.1) 6.7 (0.8) 0.039 5.5 (0.6) 0.004 < 0.001

Abbreviations: IMPT = intensity-modulated proton therapy; PSPT = passive-scattering proton therapy; SBRT = stereotactic body radiation therapy; SE = standard error; V5 = volume of total lung receiving 5 Gy; V10 = volume of total lung receiving 10 Gy; V20 = volume of total lung receiving 20 Gy.

*

Photon SBRT vs PSPT

Photon SBRT vs IMPT

PSPT vs IMPT