Table 3.
Critical normal structures | Cases | Mean maximum dose received on photon SBRT plan, Gy (SE) | Mean maximum dose received on PSPT plan, Gy (SE) | p* | Mean maximum dose received on IMPT plan, Gy (SE) | p† | p‡ |
---|---|---|---|---|---|---|---|
Aorta | 11 | 34.3 (3.8) | 27.9 (5.3) | 0.02 | 25.5 (5.7) | 0.014 | 0.292 |
Brachial plexus | 6 | 24.1 (5.3) | 11.1 (2.8) | 0.01 | 7.0 (2.8) | 0.006 | 0.007 |
Bronchial tree | 8 | 22.9 (4.3) | 18.2 (4.4) | 0.221 | 13.9 (4.1) | 0.014 | 0.093 |
Esophagus | 7 | 27.2 (5.7) | 25.8 (3.6) | 0.698 | 15.6 (4.1) | 0.005 | 0.019 |
Heart | 4 | 45.1 (8.8) | 25.5 (6.5) | 0.036 | 23.6 (7.3) | 0.032 | 0.202 |
Pulmonary vessels | 7 | 36.2 (3.4) | 24.3 (2.7) | 0.002 | 18.0 (4.7) | 0.003 | 0.115 |
Spinal cord | 9 | 20.7 (1.0) | 17.4 (1.1) | 0.02 | 12.6 (1.3) | <0.001 | 0.006 |
Trachea | 3 | 18.4 (5.3) | 19.6 (5.0) | 0.909 | 13.5 (4.6) | 0.598 | 0.215 |
Abbreviations: IMPT = intensity-modulated proton therapy; PSPT = passive-scattering proton therapy; SBRT = stereotactic body radiation therapy; SE = standard error.
Photon SBRT vs PSPT
Photon SBRT vs IMPT
PSPT vs IMPT