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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Oct 12;16(2):253–262. doi: 10.1016/j.bbmt.2009.10.004

Table 3.

Multivariate analysis of Grade 2-4 acute and chronic graft-versus-host disease

Bone marrow Acute GVHD 2-4
RR (95% CI), p-value		 Chronic GVHD
RR (95% CI), p-value
WBC
>2.34 vs. ≤2.34, 108 /kg		 0.67 (0.33-1.12), 0.11 1.05 (0.51-2.14), 0.90
CD34+
>3.62 vs. ≤3.62, 106 /kg		 0.79 (0.43-1.44), 0.43 0.94 (0.47-1.90), 0.87
CD34+ CD38−
>9.44 vs. ≤9.44, 104 /kg		 0.85 (0.47-1.55), 0.60 1.24 (0.61-2.53), 0.55
CD3+
>2.54 vs. ≤2.54, 107 /kg		 0.57 (0.31-1.06), 0.07 0.95 (0.47-1.91), 0.88
CD3+ CD4+
>1.33 vs. ≤1.33, 107 /kg		 0.93 (0.49-1.76), 0.83 0.90 (0.43-1.91), 0.79
CD3+ CD8+
>1.09 vs. ≤1.09, 107 /kg		 0.80 (0.42-1.53), 0.49 1.05 (0.50-2.21), 0.90
CD3+ CD25+
>3.05 vs. ≤3.05, 106 /kg		 0.94 (0.50-1.91), 0.85 0.76 (0.36-1.61), 0.47
CD3+ CD69+
>3.38 vs. ≤3.38, 106 /kg		 0.71 (0.37-1.36), 0.30 0.81 (0.37-1.79), 0.61
CD3+ HLA-DR+
>3.92 vs. ≤3.92, 106 /kg		 0.88 (0.47-1.62), 0.67 0.58 (0.28-1.19), 0.14
Peripheral blood progenitor cells Acute GVHD 2-4
RR (95% CI), p-value		 Chronic GVHD
RR (95% CI), p-value
WBC
>7.23 vs. ≤7.23, 108 /kg		 1.19 (0.79-1.78), 0.41 1.07 (0.69-1.66), 0.77
CD34+
>5.41 vs. ≤5.41, 106 /kg		 1.17 (0.78-1.76), 0.44 0.79 (0.51-1.22), 0.29
CD34+ CD38−
>1.54 vs. ≤1.54, 105 /kg		 1.63 (1.08-2.46), 0.02 0.98 (0.63-1.52), 0.93
CD3+
>2.37 vs. ≤2.37, 108 /kg		 1.13 (0.75-1.69), 0.57 1.21 (0.77-1.89), 0.41
CD3+ CD4+
>1.45 vs. ≤1.45, 108 /kg		 1.19 (0.79-1.78), 0.41 1.41 (0.90-2.21), 0.13
CD3+ CD8+
>8.37 vs. ≤8.37, 107 /kg		 1.08 (0.72-1.62), 0.72 1.48 (0.95-2.32), 0.09
CD3+ CD25+
>2.46 vs. ≤2.46, 107 /kg		 1.20 (0.80-1.82), 0.38 1.42 (0.91-2.23), 0.13
CD3+ CD69+
>3.55 vs. ≤3.55, 106 /kg		 1.05 (0.70-1.57), 0.83 1.10 (0.71-1.71), 0.68
CD3+ HLA-DR+
>2.18 vs. ≤2.18, 107 /kg		 0.79 (0.53-1.18), 0.25 0.89 (0.57-1.37), 0.58

Abbreviations: RR = Relative Risk; CI=Confidence Interval