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. 2010 Sep 27;6(6):569–583. doi: 10.7150/ijbs.6.569

Fig 2.

Fig 2

Morphology and histology of Smad4Co/Co;TTR-Cre embryos. (A-D) Morphology of E7.5 (A) E8.5 (B,C) and E9.5 (D) embryos. Smad4Co/Co;TTR-Cre mutant embryos were pointed by arrows. Anterior region protrudes out from yolk sac in the Smad4Co/Co;TTR-Cre mutant embryos (arrows in B-D). (E-J) Histology of E7.5 (E,F) and E8.5 (G-J) control embryos (E,G,I) and Smad4Co/Co;TTR-Cre mutant embryos (F,H,J). Arrows in E,F, and arrowhead in G,H point allantois. Arrows in H,J point to anterior truncation in the mutant embryos presented at different angles. Hf: head-fold. At least 4 Smad4Co/Co;TTR-Cre mutant embryos at each time point were analyzed.