Skip to main content
. Author manuscript; available in PMC: 2010 Oct 11.
Published in final edited form as: Restor Neurol Neurosci. 2009;27(4):359–370. doi: 10.3233/RNN-2009-0521

Fig. 8.

Fig. 8

TH expression was reduced by higher concentrations of sodium butyrate during dopaminergic differentiation. The effect of sodium butyrate on TH expression was determined by immunocytochemistry. (A) The morphology of colonies and neural-like rosettes was changed, and TH immunoreactivity (red) was reduced, by 2 mM of sodium butyrate treatment at the early stage of differentiation. (B) The number of colonies containing TH-positive cells was decreased significantly, as compared to the control group, *** indicates ρ< 0.001. (C) TH expression was reduced by 0.2 and 2.0 mM sodium butyrate treatment at the later stage of differentiation. (D) The reduction in TH expression by 0.2 and 2.0 mM concentrations of sodium butyrate was statistically significant. ** and *** indicate ρ< 0.01 and ρ< 0.001 respectively. Data shown are means ± SEM. Scale bar = 200μm.