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. Author manuscript; available in PMC: 2010 Oct 11.
Published in final edited form as: Laryngoscope. 2009 Jul;119(7):1258–1264. doi: 10.1002/lary.20239

TABLE III.

Statistical Analysis of SNP.

Gene Symbol (Location) SNP Chr Position in Base Pairs From Chr Start Alleles HWE P Value* OR (CI) OR P Value
IL-10 (−592) rs1800895 1 205013095 A/G .87
IL-10 (−819) rs1800894 1 205013289 A/G .0009
IL-10 (−1082) rs1800896 1 205013520 A/G .64
IL-1α (+4845) rs17561 2 113253694 G/T .51
IL-1α (−819) rs3783521 2 113260048 C/T .38
IL-β (+3935) rs1143634 2 113306861 C/T .73
IL-β (−511) rs3087258 2 113311342 C/T .0001
CD14 (−159) rs2569190 5 139993100 A/G .16
TNF-α (−308) rs1800629 6 31651010 A/G .93 1.86 (1.14,3.09)§ .01
IL-6 (−174) rs13447445 7 22733281 C/G
IFNγ (−874) rs2430561 12 66838789 A/T .71
CCL2 (−2518) rs3917882 17 29603912 A/G .93
CCL5 (−403) rs2107538 17 31231893 C/T .81
TGF-β1 (509) rs11466315 19 46551616 C/G .86

SNP = single-nucleotide polymorphism; Chr = chromosome; HWE = Hardy Weinberg equilibrium; OR = odds ratio; CI = confidence interval; rs = reference SNP; IL = interleukin; TNF = tumor necrosis factor; IFN = interferon; TGF = transforming growth factor; CCL = cysteinyl chemokine ligand.

*

Fisher exact test P values for tests of Hardy Weinberg equilibrium proportions in controls.

Confidence interval includes 1.00/P values not significant.

Risk allele.

§

Dominant genetic model.

SNP is monomorphic.