Table 7.

Accelerated Pd(II)-catalyzed C–H olefination of phenylacetic acid substrates 1–10.^a,^b

Product	Ligand	% Conv.
	---	7c
	BQ	3c
	Ac-Ile-OH	>99 (96)
	---	25c
	BQ	7c
	Ac-Ile-OH	98 (97)
	---	2
	BQ	1
	Ac-Ile-OH	>99 (98)
	---	64
	BQ	9
	Ac-Ile-OH	88 (83)d
	---	93 (92)
	BQ	12
	Ac-Ile-OH	>99 (95)
	---	6
	BQ	2
	Ac-Ile-OH	>99 (99)
	---	8e
	BQ	3e
	Ac-Ile-OH	>99 (99)e
	---	0
	BQ	0
	Ac-Ile-OH	72 (70)f
	---	10
	BQ	5
	Ac-Ile-OH	>99 (98)
	---	44g
	BQ	23
	Ac-Ile-OH	>99 (94)

^a5 mol% BQ (when used), 10 mol% Ac-Ile-OH (when used).

^bThe conversion was determined by ¹H NMR analysis of the crude reaction mixture. Isolated yield is given in parentheses.

^cAverage of three trials.

^dAn additional 11% of the di-ortho-olefinated product was observed by ¹H NMR.

^e6 h.

^fAn additional 6% of the decarboxylated product was formed.

^gAn additional 4% of a positional isomer was formed.