Table 1.

Most common adverse events (AEs) in healthy volunteers and patients.55,63,64,66

	Healthy volunteers	Patients
Total No. of subjects	42	932
Total No. of subjects with at least one AE	21	507
Total No. of subjects with at least one serious AE	0	63
Dysgeusia	17	30
Nausea	10	113
Headache	10	68
Abdominal pain	2	*
Vomiting	1	61
Diarrhea	1	62
Constipation	0	33
Hypersensitivitya	0	49
Infusion-site reaction	1	48

^aIncluding rash and pruritus.

Reprinted with permission from Barbour A, Schmidt S, Rand KH, Derendorf H. Ceftobiprole: a novel cephalosporin with activity against Gram-positive and Gram-negative pathogens, including methicillin-resistant Staphylococcus aureus (MRSA). Int J Antimicrob Agents. 2009;34:1–7.56 Copyright © 2009 Elsevier.