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. Author manuscript; available in PMC: 2011 Sep 14.
Published in final edited form as: Biochemistry. 2010 Sep 14;49(36):7821–7829. doi: 10.1021/bi100726n

Figure 6.

Figure 6

A) Proposed structural organization and assembly of TRUSS. a) Primary structure organization. The putative leucine zipper is dark blue. b) Proposed tertiary organization of the N-terminal, central and C-terminal regions. c) Proposed position of the TNF-R1 and TRAF2 binding interface. d) Proposed organization of the TRUSS homotrimer. B. Alignment and conservation of the putative C-terminal leucine zipper sequences of vertebrate TRUSS. *The Entrez gene entries for these sequences only show isoform “b” which lacks an 8 residue sequence that arises by alternative splicing. Consequently, for comparison to the position of the second leucine like zipper, the numeric positions of the sequences are 8 residues shorter than those for the longer “a” isoform.