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. 2010 Nov;51(11):3103–3116. doi: 10.1194/jlr.M005041

Fig. 5.

Fig. 5.

Glucose, but not maltose, alters PPARα interaction L-FABP. Far UV (UV) circular dichroic (CD) spectra of PPARα and L-FABP in the absence (A-H, •) and presence (○) of glucose compared with the theoretically obtained spectrum for PPARα and L-FABP in the presence of glucose if no interaction occurred between the proteins (▾) (A) 6 μM glucose, (B) 60 μM glucose, (C) 6 μM maltose (○) and 60 μM maltose (▾), (D) 6 mM glucose, (E) 20 mM glucose, (G) 6 mM maltose (○) and 20 mM maltose (▾), (G) 11 μM G-1-P, and (H) 0.2 mM G-6-P. Each spectrum represents an average of ten scans for a given representative spectrum, n = 3–4. G-1-P, glucose-1-phosphate; G-6-P, glucose-6-phosphate; L-FABP, liver fatty acid binding protein; PPARα, peroxisome proliferator-activated receptor alpha.