Table 1. Functional categorization of all genes immediately flanking the piggyBac insertion loci shows significant enrichment for genes involved in nucleic acid metabolism/nucleic acid binding/transcription in the severely attenuated mutants (P<0.05).

Functional Category	Number of genes affected in each category
	Severely attenuated	Moderately attenuated	Non-attenuated
Biochemical pathways/protein metabolism/protein modification	10	19	27
Conserved proteins with unknown function	13	23	44
Exported proteins	3	10	12
Membrane/structural proteins/trafficking/signal transduction	5	6	16
Nucleic acid metabolism/nucleic acid binding/transcription	10	5	11
Total	41	63	110