Table 3. List of genes involved in nucleic acid binding/nucleic acid metabolism/transcription identified to be crucial for intraerythrocytic development of Plasmodium falciparum.
Gene ID | PlasmoDB Annotation | Percent attenuation |
PF13_0318 | RNA binding protein | 72 |
PFE0570w | RNA pseudouridylate synthase | 57 |
PFF1100c | Transcription factor with AP2 domain(s) | 56 |
PF13_0235 | Transcription factor with AP2 domain(s) | 50 |
PFD0180c | CGI-201 protein, short form | 50 |
MAL8P1.104 | CAF1 family ribonuclease | 46 |
PFL1345c | RNA pseudouridylate synthase | 46 |
PFL1350w | Histone acetyltransferase | 46 |
PF11_0347 | Conserved Plasmodium protein | 43 |
MAL8P1.19 | RNA helicase | 41 |