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Tetanic stimulation of the tibialis anterior (TA) muscle of 4 month old mice shows a precipitous decay in tetanic force in oim/oim (right, arrowhead) and mild decay in +/oim (center, arrowhead) compared to wt (left) mice (300 ms duration, 150 Hz). In addition, oim/oim mice were unable to sustain Po contraction during the entire 300 ms stimulation period (right, asterisk).
