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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Aug 26;20(21):6258–6261. doi: 10.1016/j.bmcl.2010.08.096

Table 2. Ki values of 1, 2a, 2b, and 3 for rat nNOS and human nNOS.

Kia(nM) selectivity
inhibitor
rat nNOS human nNOS rat/human



1 7 50 7.1
2a 50 290 5.8
2b 220 1,800 8.2
3 110 490 4.5
a

The Ki values represent at least duplicate measurements with standard deviations of ±10%.