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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Clin Biochem. 2010 Aug 14;43(16-17):1269–1277. doi: 10.1016/j.clinbiochem.2010.07.027

Figure 1.

Figure 1

Labeling of 3-carbon-, 4-carbon and 5-carbon metabolic intermediates from [1,2-13C2]-glucose or [2, 3-13C2]-lactate through the TCA cycle. Open circles represent 12C carbons and shaded circles represent 13C carbons. The direction of flow of TCA cycle substrates is indicated by the numbered arrow. Pyr stands for pyruvate, OAA for oxaloacetate and KG for ketoglutarate.