Table 2.

Percent difference (95% CI) in inflammatory markers per standard deviation increase of neighborhood domain (deprivation, problems, safety, and cohesion) at the MESA baseline exam.

	Model 1a		Model 2b		Model 3c		Model 4d		Model 5e
	Percent difference	95% CI	Percent difference	95% CI	Percent difference	95% CI	Percent difference	95% CI	Percent difference	95% CI
Fibrinogen
Deprivation score	2.7	2.1, 3.3	2.1	1.5, 2.7	1.3	0.7, 1.9	0.9	0.3, 1.5	0.7	0.1,1.3
Problems score	2.0	1.4, 2.5	1.7	1.2, 2.3	1.1	0.5, 1.7	0.9	0.3, 1.5	0.7	0.2,1.3
Safety score	−2.2	−2.8, −1.6	−1.8	−2.4, −1.3	−1.1	−1.7, −0.6	−0.9	−1.5, −0.4	−0.7	−1.3,−0.1
Cohesion score	−0.9	−1.4, −0.3	−0.6	−1.2, 0.0	−0.6	−1.1, 0.0	−0.5	−1.0, 0.1	−0.4	−1.0,0.0
IL-6
Deprivation score	6.8	4.8, 8.8	4.6	2.5, 6.7	2.2	0.3, 4.2	0.5	−1.5, 2.5	0.3	−1.5,2.2
Problems score	5.5	3.5, 7.5	4.8	2.8, 6.8	1.3	−0.6, 3.2	0.6	−1.3, 2.5	−0.4	−2.2,1.4
Safety score	−6.6	−8.5, −4.8	−5.4	7.2, −3.4	−3.2	−5.0, −1.3	−2.2	−4.0, −0.3	−1.5	−3.3,0.3
Cohesion score	−2.1	−4.0, −0.2	−1.3	−3.2, 0.6	−1.7	−3.5, 0.1	−1.4	−3.2, 0.4	−1.5	−3.2,0.2
CRP
Deprivation score	9.0	5.3, 12.8	5.5	1.7, 9.4	−0.8	−4.0, 2.5	−3.6	−6.9, −0.3	−3.0	−6.2,0.2
Problems score	9.8	6.1, 13.6	8.6	4.9, 12.4	0.4	−2.7, 3.7	−0.6	−3.8, 2.6	−2.0	−5.0,1.1
Safety score	−8.2	−11.5, −4.8	−6.4	−9.8, −2.9	−0.5	−3.7, 2.8	1.1	−2.2, 4.5	1.9	−1.2,4.9
Cohesion score	−0.8	−4.1, 2.7	0.3	−3.1, 3.8	0.0	−3.1, 3.2	0.4	−2.7, 3.6	−0.2	−3.1,2.8

Using mixed linear regression models with random intercept at the census tract level

^aModel 1: Adjusted for age and sex

^bModel 2: Adjusted for age, sex, family income and education

^cModel 3: Adjusted for age, sex and race/ethnicity

^dModel 4: Adjusted for age, sex, family income, education and race/ethnicity

^eModel 5: Adjusted for age, sex, family income, education, race/ethnicity, BMI, waist circumference, physical activity, dietary pattern score, smoking, alcohol intake, recent acute infection, medication use, impaired glucose tolerance, and diabetes