Table 3.

Mean difference in annual change (95% CI) in IL-6 levels (pg/mL) per standard deviation increase of neighborhood domain in a sub-sample of MESA participants.

Neighborhood characteristic	Model 1^a		Model 2^b		Model 3^c		Model 4^d		Model 5^e

	Diff- erence	95% CI	Diff- erence	95% CI	Diff- erence	95% CI	Diff- erence	95% CI	Diff- erence	95% CI
Deprivation score	0.06	0.02, 0.09	0.05	0.02, 0.08	0.05	0.02, 0.09	0.06	0.02, 0.09	0.05	0.02,0.09
Problems score	0.03	0.00, 0.06	0.03	0.00, 0.06	0.04	0.00, 0.07	0.04	0.00, 0.07	0.02	−0.01,0.05
Safety score	−0.05	−0.09, −0.02	−0.04	−0.08, −0.01	−0.05	−0.08, −0.01	−0.04	−0.07, −0.01	−0.03	−0.07,0.00
Cohesion score	−0.01	−0.04, 0.03	0.00	−0.04, 0.03	−0.01	−0.04, 0.02	−0.01	−0.04, 0.02	0.00	−0.02,0.03

Using mixed linear regression models with random intercept at the census tract level; mean follow-up time (range): 3.89 years (1.95–6.20)

Model 1: Adjusted for age and sex

Model 2: Adjusted for age, sex, family income and education

Model 3: Adjusted for age, sex and race/ethnicity

Model 4: Adjusted for age, sex, family income, education and race/ethnicity

Model 5: Adjusted for age, sex, family income, education, race/ethnicity, and at baseline: BMI, waist circumference, physical activity, dietary pattern score, smoking, alcohol intake, recent acute infection, medication use, impaired glucose tolerance, and diabetes