Table 1. Physical and Biochemical parameters in young and aging FBN rats of both sexes.

Body weight (g) and heart weight (g) were measured for all animals in each group. The biochemical parameters were measured using the plasma collected from all age groups of FBN rats in both sexes. The data is expressed as mean ± SEM. One-way ANOVA followed by Bonferroni test was performed on all age groups compared to the young (6 mo) controls. TC: Total Cholesterol, TG: Triglycerides, HDL: High Density Lipoprotein.

	Female			Male
	6 mo	26 mo	30 mo	6 mo	30 mo	36 mo
Body Weight (g)	230.5±14.1	294.5±38.2****	320.4±20.6****	422.5±42.3	560.7±11.3***	450.8±35.2
Heart Weight (g)	0.74±0.03	0.98±0.03****	1.16±0.03****	1.08±0.03	1.63±0.09***	1.70±0.13**
Plasma Lipid Profile
TC (mg/dl)	96.3±8.01	97.1±6.54	97.4±7.91	102.7±3.15	101.2±2.54	100.7±2.92
TG (mg/dl)	56.3±5.09	70.4±9.29	107.9±7.84***	75.2±6.50	87.5±7.21	101.4±8.97
HDL (mg/dl)	18.9±0.87	28.3±9.17	33.4±1.43*	16.3±1.32	17.1±2.12	22.7±3.57**
Circulating Adipokines
Adiponectin	7.48±1.34	10.09±1.00**	9.30±0.76	9.51±1.32	10.26±0.57**	14.56±3.08***
(pg/ml)

^*p< 0.05;

^**p< 0.01;

^***p< 0.005;

^****p< 0.001.