Table 2.
Most commonly reported adverse eventsa for safety analysis set
| Adverse Event, n (%) | OSA (n = 468) | SWD (n = 108) | Narcolepsy (n = 155) | Total (N = 731) |
|---|---|---|---|---|
| Headache | 114 (24) | 20 (19) | 46 (30) | 180 (25) |
| Nasopharyngitis | 71 (15) | 19 (18) | 33 (21) | 123 (17) |
| Insomnia | 76 (16) | 10 (9) | 13 (8) | 99 (14) |
| URTI | 55 (12) | 13 (12) | 8 (5) | 76 (10) |
| Nausea | 38 (8) | 7 (6) | 23 (15) | 68 (9) |
| Sinusitis | 52 (11) | 4 (4) | 8 (5) | 64 (9) |
| Arthralgia | 47 (10) | 4 (4) | 8 (5) | 59 (8) |
| Anxiety | 39 (8) | 9 (8) | 9 (6) | 57 (8) |
| Influenza | 39 (8) | 9 (8) | 7 (5) | 55 (8) |
| Back pain | 41 (9) | 5 (5) | 7 (5) | 53 (7) |
| Dry mouth | 30 (6) | 7 (6) | 12 (8) | 49 (7) |
| Dizziness | 31 (7) | 2 (2) | 14 (9) | 47 (6) |
| Cough | 23 (5) | 6 (6) | 13 (8) | 42 (6) |
| Hypertension | 31 (7) | 3 (3) | 8 (5) | 42 (6) |
OSA refers to obstructive sleep apnea; SWD, shift work disorder; URTI, upper respiratory tract infection.
a
Events reported by > 5% of the safety analysis set.