Table 1.
N a | Meansb ± S.E. | Odds Ratio | C.I. | P-value | |
---|---|---|---|---|---|
Gender | |||||
Womanc | 31 | 1.2 ± 0.3 | 1 | ||
Male | 73 | 1.3 ± 0.2 | 0.65 | 0.19–2.16 | .480 |
Age (years) | |||||
Per unit | 104 | 1.3 ± 0.2 | 1.02 | 0.97–1.06 | .516 |
Smoking habit | |||||
Nonsmokerc | 21 | 0.8 ± 0.4 | 1 | ||
Former smoker | 44 | 1.0 ± 0.3 | 1.60 | 0.39–6.58 | .517 |
Smoker <40 years | 11 | 1.5 ± 0.7 | 2.38 | 0.41–13.90 | .336 |
Smoker ≥40 years | 27 | 2.0 ± 0.5 | 5.28 | 1.00–27.72 | .049 |
Status | |||||
Controlsc | 40 | 1.0 ± 0.3 | 1 | ||
Benign lung disease | 30 | 1.3 ± 0.4 | 0.93 | 0.28–3.03 | .898 |
Lung cancer | 34 | 1.5 ± 0.4 | 1.17 | 0.39–3.47 | .783 |
XRCC1 Arg194Trp | |||||
Arg/Argc | 87 | 1.1 ± 0.2 | 1 | ||
Arg/Trp | 11 | 2.6 ± 1.1 | 4.08 | 0.77–21.48 | .098 |
XRCC1 Arg399Gln | |||||
Arg/Argc | 37 | 0.9 ± 0.2 | 1 | ||
Arg/Gln | 47 | 1.4 ± 0.3 | 0.93 | 0.36–2.39 | .882 |
Gln/Gln | 12 | 1.8 ± 1.0 | 1.32 | 0.34–5.18 | .689 |
XRCC3 Thr241Met | |||||
Thr/Thrc | 40 | 1.5 ± 0.4 | 1 | ||
Thr/Met | 41 | 1.2 ± 0.3 | 0.38 | 0.15–0.97 | .043 |
Met/Met | 19 | 0.7 ± 0.4 | 0.17 | 0.05–0.61 | .006 |
Number of risk alleles | |||||
0-1c | 25 | 0.8 ± 0.4 | 1 | ||
2 | 31 | 1.0 ± 0.3 | 0.92 | 0.31–2.69 | .877 |
3-4 | 38 | 2.0 ± 0.5 | 4.1 | 1.28–13.09 | .009 |
aSome figures do not add up to the total because of missing values.
bLevels per 108 normal nucleotides.
cReference level.