Table 2.
Means of DNA adducts ± standard error (SE) case-control status considering the number of DNA repair risk alleles plus the parameter estimates of the multivariate regression model.
N a | Meansb ± S.E. | Odds Ratio | C.I. | P-value | |
---|---|---|---|---|---|
0-1 risk alleles | |||||
Smoking habit | |||||
Nonsmokerc | 6 | 1.7 ± 1.5 | 1 | ||
Former smoker | 12 | 0.4 ± 0.1 | 0.08 | 0.00–9.76 | .302 |
Smoker <40 years | 2 | 0.3 ± 0.2 | 0.33 | 0.00–67.26 | .686 |
Smoker ≥40 years | 5 | 1.3 ± 1.1 | 0.16 | 0.00–27.05 | .480 |
Status | |||||
Controlsc | 13 | 1.3 ± 0.7 | 1 | ||
Benign lung disease | 4 | 0.4 ± 0.1 | 1.23 | 0.08–19.30 | .884 |
Lung cancer | 8 | 0.5 ± 0.2 | 0.43 | 0.05–4.00 | .458 |
| |||||
2 risk alleles | |||||
Smoking habit | |||||
Nonsmokerc | 7 | 0.4 ± 0.1 | 1 | ||
Former smoker | 10 | 0.7 ± 0.4 | 2.46 | 0.12–50.98 | .560 |
Smoker <40 years | 5 | 0.8 ± 0.6 | 0.86 | 0.03–28.37 | .933 |
Smoker ≥40 years | 9 | 1.7 ± 0.6 | 20.91 | 0.62–709.04 | .091 |
Status | |||||
Controlsc | 12 | 0.5 ± 0.2 | 1 | ||
Benign lung disease | 7 | 1.1 ± 0.6 | 1.11 | 0.12–10.00 | .928 |
Lung cancer | 12 | 1.3 ± 0.5 | 2.39 | 0.25–22.62 | .447 |
| |||||
3-4 risk alleles | |||||
Smoking habit | |||||
Nonsmokerc | 5 | 0.4 ± 0.2 | 1 | ||
Former smoker | 20 | 1.7 ± 0.7 | 9.47 | 0.52–173.16 | .130 |
Smoker ≥40 years | 9 | 2.9 ± 1.3 | 36.38 | 1.17–1132.84 | .040 |
Status | |||||
Controlsc | 12 | 1.5 ± 0.6 | 1 | ||
Benign lung disease | 15 | 2.1 ± 0.9 | 0.45 | 0.06–3.69 | .460 |
Lung cancer | 11 | 2.3 ± 1.1 | 4.54 | 0.33–62.93 | .259 |
aSome figures do not add up to the total because of missing values.
bLevels per 108 normal nucleotides.
cReference level.