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Plasma total cholesterol (Panel A) and triglycerides (Panel B) in C57, ApoE and LDLR mice at 12–13 weeks or 22–23 weeks of age. Data are presented as mean±SEM, n=8 animals for each group. * p<0.05 vs. C57 at that age; † p<0.05 vs. ApoE at that age.