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. 2010 Aug 27;38(18):e178. doi: 10.1093/nar/gkq622

Table 3.

A survey of alternative exon splicing events identified with MapSplice junctions

Coverage Alternative exon events
Mutual Excl.
Sample Skipped Exon Alt. Start Alt. End
Inline graphic1 BAS 6880 6700 7474 442
BAS 7365 7611 8005 454
SUM 5574 5690 6359 353
SUM 5491 5701 6451 337
LUM 6523 7326 7777 387
LUM 6321 6928 7625 355
MCF 6776 6338 7350 472
MCF 6352 6063 7083 444
Inline graphic2 BAS 2726 2144 2564 101
BAS 2941 2529 2689 111
SUM 2271 2098 2347 103
SUM 2277 2096 2359 95
LUM 2599 2542 2574 95
LUM 2333 2031 2387 86
MCF 2949 2410 2778 129
MCF 2669 2331 2588 109
Inline graphic5 BAS 651 476 614 26
BAS 718 522 641 23
SUM 644 538 643 25
SUM 623 528 656 25
LUM 618 538 582 22
LUM 503 386 528 21
MCF 815 686 780 30
MCF 757 656 735 22

Four different types of alternative splicing events involving at least two splice junctions were identified in each sample. They are exon skipping events, alternative 3′-end, alternative 5′ start and mutually exclusive exons. Alternative splicing events were examined at different expression levels, only junctions with coverage larger than the given threshold (1, 2, 5) were considered. In general, there are about 35% exon skipping events, 30% alternative 5′ start events, 34% alternative 3′-end events and 1.3% mutually exclusive exon events.