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Overexpression of hNEDL1 affected the locomotion and rotarod performance. (a) Behavior (locomotion) in the mice was evaluated; each value (counts per 10 min) is the mean ± SEM (n = 11 ~ 12; *P < .05; **P < .01). (b) The rotarod performance of wild-type (white bar: n = 12) and hNEDL1-Tg mice (black bar: n = 11) from the age of six mounths to fifteen months. Data are mean ± SEM (*P < .05; **P < .01).
